PENGARUH SINBIOTIK KEFIR TEPUNG PISANG BATU (Musa balbisiana) TERHADAP KADAR GLUKOSA DARAH TIKUS SINDROM METABOLIK
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Abstract
Sindrom metabolik diawali resistensi insulin yang ditandai hiperglikemia. Sinbiotik kefir tepung pisang batu (M. balbisiana) menurunkan kadar glukosa darah. Penelitian ini dilakukan untuk menganalisis pengaruh sinbiotik kefir tepung pisang batu (M. balbisiana) terhadap kadar glukosa darah tikus sindrom metabolik. Penelitian ini menggunakan 24 tikus Sprague Dawleyyang dibagi menjadi empat kelompok, yaitu kontrol negatif yang diberi pakan standar, kontrol positif yang diberi high fat fructose diet(HFFD), dan perlakuan I (PI) serta perlakuan II (PII) yang masing-masing diberi HFFD dan sinbiotik kefir tepung pisang batu (M.balbisiana) 1,8 mL 200 g־ ¹BB tikus per hari (PI) dan 3,6 mL 200 g־ ¹BB tikus per hari (PII) selama tiga minggu. Hasil menunjukkan perbedaan kadar glukosa darah setelah pemberian sinbiotik kefir tepung pisang batu (M.balbisiana) secara signifikan (p=0,000). Sinbiotik kefir tepung pisang batu (M. balbisiana) menurunkan kadar glukosa darah tikus sindrom metabolik.
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