PEMBUATAN RADIONUKLIDA MOLIBDENUM-99 (99Mo) HASIL AKTIVASI NEUTRON DARI MOLIBDENUM ALAM UNTUK MEMPEROLEH TEKNESIUM-99m (99mTc)

Abstract

Uranium usage restriction causes the hospitals in Indonesia difficult to obtain the supply of ^99mTc. At Present, ^99mTc is obtained from molybdenum as a uranium fission product. Production of ⁹⁹Mo radionuclide resulted from neutron activated natural molybdenum (MoO₃) in G.A Siwabessy reactor could be used as an alternative method for producing ^99mTc. The aim of this research is synthesized of   ⁹⁹Mo radionuclide from neutron activated natural molybdenum (MoO₃) to obtain ^99mTc. The five grams of MoO₃ powder was packed in a quartz ampule and inserted into inner capsule then also inserted into outer capsule as a target material. It was irradiated in G.A Siwabessy reactor for 100hours. Based on theoritical calculation, about 65 % of maximum ⁹⁹Mo activity could be recovered. After irradiation, MoO₃ was dissolved by NaOH 4 M solution, so it was natrium molybdate (Na₂MoO₄) solution. ⁹⁹Mo and ^99mTc radionuclide were analyzed using gamma spectrometer. ⁹⁹Mo radionuclide was detected on Na₂MoO₄ solution as product that had specific activity of 0.81 Ci ⁹⁹Mo/ g Mo. ^99mTc as daughter radionuclide was separated from ⁹⁹Mo as parent radionuclide using separated column containing zirconium-based material (ZBM) as ⁹⁹Mo adsorbent. ^99mTc radionuclide has been successfully separated using ZBM column although recovery of ^99mTc was quite low in which approximately 52 to 71 %. The ^99mTc radionuclide was recovered in the form of sodium pertechnetate (NaTcO₄) solution.