SYNTHESIS AND CHARACTERIZATION OF MAGNETIC-HYDROXY APATITE COMPOSITE USINGONE SPOT COPRECIPITATION METHOD
DOI:
https://doi.org/10.17146/jsmi.2017.18.2.4171Keywords:
Composite, Magnetite, Maghemite, Hydroxyapatite, One-spot coprecipitationAbstract
SYNTHESIS AND CHARACTERIZATION OF MAGNETIC-HYDROXY APATITE COMPOSITE USINGONE SPOT COPRECIPITATION METHOD. Nanocomposite of magnetic-hydroxyapatite (MHAP) has the potential to be developed as a biocompatible-biodegradable material for bone cancer diagnosis and therapy. In this study, such composite materials have been successfully synthesized by one-spot coprecipitation method and ultrasonic dispersion. The mass ratio between magnetic and hydroxyapatite fraction were varied to 30:70 (K30), 40:60 (K40) and 50:50 (K50). X-Ray Diffractometer, Transmission Electron Microscope, Fourier Transform-Infrared Spectrometer and Vibrating Sample Magnetometer were used for characterizing the properties of MHAP composite. X-Ray Diffraction pattern reveals the presence of magnetic and HAP phases, confirm the establishment of MHAP composite system. TEM image and FT-IR spectra shows the spherical morphology of magnetic nanoparticles with a size of ~ 10 nm entrapped within HAP nanorod structure without any chemical bonding between the two phase.With such physical composite mechanismand higher energy induce by ultrasonic dispersion process, magnetic fraction of even 50% mass fraction could still be loaded into HAP matrix and provide maximum magnetisation value of 34.6 emu/g. This magnetization value is higher than the result of another study of MHAP synthesis, giving better prospect for bone cancer diagnosis and therapy.
Downloads
References
. M. A. Velasco, C. A. Narváez-Tovar, and D. A. Garzón-Alvarado. “Design, Materials, and Mechanobiology of Biodegradable Scaffolds for Bone Tissue Engineering.” Biomed Res. Int., vol. 2015, pp. 1-21, 2015.
. F. Foroughi, S. A. Hassanzadeh-Tabrizi, and J. Amighian. “Microemulsion Synthesis and Magnetic Properties of Hydroxyapatiteencapsulated nano CoFe2O4.” J. Magn. Magn. Mater., vol. 382, pp. 182-187, 2015.
. V. C. Nguyen and Q. H. Pho. “Preparation of Chitosan Coated Magnetic Hydroxyapatite Nanoparticles and Application for Adsorption of
Reactive blue 19 and Ni2+ ions.” Sci. World J., vol. 2014, pp. 1-9, 2014.
. S. Murakami, T. Hosono, B. Jeyadevan, M. Kamitakahara, and K. Ioku. “Hydrothermal Synthesis of Magnetite/Hydroxyapatite Composite
Material for Hyperthermia Therapy for Bone Cancer.” J. Ceram. Soc. Japan, vol. 116, no. 9, pp. 950-954, 2008.
. T. Iwasaki, R. Nakatsuka, K. Murase, H. Takata, H. Nakamura, and S. Watano. “Simple and Rapid Synthesis of Magnetite/Hydroxyapatite Composites for Hyperthermia Treatments Via A Mechano Chemical Route.” Int. J. Mol. Sci., vol. 14, no. 5, pp. 9365-9378, 2013.
. W. Wu, Z. Wu, T. Yu, and C. Jiang. “Recent SssssProgress on Magnetic Iron Oxide Nanoparticles : Synthesis, Surface Functional Strategies and Biomedical Applications,” Sci. Technol.Adv. Mater., vol. 16, no. 2, pp. 1-43, 2015.
. A. Inukai et al. “Synthesis and Hyperthermia Property of Hydroxyapatit Eferrite Hybrid Particles by Ultrasonic Spray Pyrolysis.” J. Magn. Magn. Mater., vol. 323, no. 7, pp. 965-969, 2011.
. N. Wakiya, M. Yamasaki, T.Adachi,A. Inukai, and N. Sakamoto. “Preparation of HydroxyapatiteFerrite Composite Particles by Ultrasonic Spray Pyrolysis.” Mater. Sci. Eng. B, vol. 173, no. 1-3, pp. 195-198, 2010.
. F. Izumi and T. Ikeda. “A Rietveld-Analysis Programm RIETAN-98 and Its Applications to Zeolites.” Mater. Sci. Forum, vol. 321-324, pp. 198-205, 2000.
. Z. Danková and V. Zelenak. “Influence of Heat Treatment on Phase Transformation of Clay-Iron oxide composite.” J. Alloys Compd., vol. 511, pp. 63-69,2012.
. M. Manoj, R. Subbiah, D. Mangalaraj, N. Ponpandian, C. Viswanathan, and K. Park. “Influence of Growth Parameters on The Formation
of Hydroxyapatite (HAp) Nanostructures and Their Cell Viability Studies.” Nanobiomedicine, vol. 2, no. 2, pp. 1-11, 2015.
. M. Wojasiński, E. Duszyńska, and T. Ciach. “Lecithin-Based Wet Chemical Precipitation of Hydroxyapatite Nanoparticles.” Colloid Polym.
Sci., vol. 293, no. 5, pp. 1561-1568, 2015.
. P. Ptacek. “Introduction to Apatites.” in Apatites and their Synthetic Analogues-Synthesis, Structure, Properties and Applications, INTECH,
pp. 1-59, 2016.
. M. Okuda et al. “Structural Analysis of Hydroxyapatite Coating on Magnetite Nanoparticles Using Energy Filter Imaging and Electron Tomography.” J. Electron Microsc. (Tokyo)., vol. 59, no. 2, pp. 173-179, 2010.
. F. Heidari, M. E. Bahrololoom, D. Vashaee, and L. Tayebi. “In Situ Preparation of Iron Oxide Nanoparticles in Natural Hydroxyapatite/Chitosan Matrix for Bone Tissue Engineering Application.” Ceram. Int., vol. 41, pp. 3094-3100, 2015.
. M. Nakaya, R. Nishida, and A. Muramatsu. “Size Control of Magnetite Nanoparticles in Excess Ligands as a Function of Reaction Temperature and Time.” Molecules, vol. 19, no. 8, pp.11395-11403, 2014.
. R. A. Ortega and T. D. Giorgio. “A Mathematical model of Superparamagnetic Iron Oxide Nanoparticle Magnetic Behavior to Guide The
Design of Novel Nanomaterials.” J. Nanoparticle Res., vol. 14, no. 12, 2012.
. D. Gopi, M. T.Ansari, E. Shinyjoy, and L. Kavitha. “Synthesis and Spectroscopic Characterization of Magnetic Hydroxyapatite Nanocomposite Using Ultrasonic Irradiation.” Spectrochim.Acta - Part A Mol. Biomol. Spectrosc., vol. 87, pp. 245-250, 2012.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
