MODELING THE FORMATION OF POLYLACTIDE MICROSPHERES

Authors

  • Indra Gunawan Technology Center of Industrial Nuclear Materials - BATAN, Kawasan Puspiptek, Serpong 15314, Tangerang
  • Aloma K. K. a Technology Center of Industrial Nuclear Materials - BATAN, Kawasan Puspiptek, Serpong 15314, Tangerang
  • Sudirman Technology Center of Industrial Nuclear Materials - BATAN, Kawasan Puspiptek, Serpong 15314, Tangerang

DOI:

https://doi.org/10.17146/jsmi.2007.8.2.4780

Keywords:

dimensional analysis, principle of similarity, microspheres

Abstract

MODELING THE FORMATION OF POLYLACTIDE MICROSPHERES. Biodegradable polylactide microspheres have been developed from a dispersion solution of polylactide in chloroform with polyvinyl alcohol in water. The present paper focuses on developing an understanding of microspheres formation through simple dimensional analysis and principle of system similarity for microstructure observation of microsphere diameter formed. Theoretical correlation between microspheres diameter and agitation rate was derived with the concept of similarity. While the empirical correlation between Weber (We) number and microspheres diameter was derived from dimensional analysis of variables that is useful for prediction of microspheres diameter to support Holmium powder. The empiric equation of the microspheres diameter forming as a function of essential process parameters is: ln (dm/dp) = -4.81 + 0.593 ln We.

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References

. ORDER, S.E., SIEGEL, J.A., LUSTIG, R.A., PRINCIPATO, T.E., ZEIGER, L.S., JOHNSON, E., ZHANG, H., LANG, P., PILCHIK, N.B., METSZ, J., DENITTIS,A., BOERNER, P., BEUERLEIN and G., WALLNER, P.E., Int. J. Radiation Oncology Biol. Phys., 30 (1994) 715-720

. NIJSEN, F., ROOK, D., BRANDT, C., MEIJER, R., DULLENS, H., ZONNEBERG, B., KLERK, J.D., RICJK, P.V., HENNINK, W. and SCHIP, F.V.H., Eur. J. Nucl. Med., 28 (2001) 743-749

. SUDARYANTO, SUDIRMAN, ALOMA KARO KARO, INDRA GUNAWAN, TRI DARWINTO, dan WAHYUDIANINGSIH, Pembuatan Microsphere Berbasis Polimer Biodegradable Polilaktat, Prosiding Simposium Nasional Polimer IV, Jakarta, (2003) 181-188

. http://www.brace.de

. INDRA GUNAWAN, TRI DARWINTO, SUDARYANTO dan ARI HANDAYANI, Jurnal Sains dan Teknologi Nuklir Indonesia, 4 (4) (2003) 1- 8

. INDRA GUNAWAN, TRI DARWINTO dan SUDARYANTO, Jurnal Sains Materi Indonesia, 5 (3) (2004) 44-47

. JOHSTONE, R.E. and THRING, M.W.,Pilot Plants, Models, and Scale-Up Methods in Chemical Engineering, McGraw Hill Book Co., Inc., New York,(1957)

. PERRY, R.H. and GREEN, D., Hand Book for Chemical Engineers, McGraw Hill Book Co., New York,(1985)

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Published

28-02-2007

How to Cite

Indra Gunawan, Aloma K. K., & Sudirman. (2007). MODELING THE FORMATION OF POLYLACTIDE MICROSPHERES. Jurnal Sains Materi Indonesia, 8(2), 125–128. https://doi.org/10.17146/jsmi.2007.8.2.4780